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Hydrogels – Which One to Choose?

Fitodenta hydrogels – essential solutions for effective infection control

Used in everyday dental practice, hydrogels support faster and safer tissue healing and help reduce the risk of complications. The Fitodenta hydrogel system is designed to address a wide range of clinical situations – from targeted therapy to preventive use before and after procedures.

Which one to choose?

Hydrogel with POVIDONE-IODINE (+ hyaluronic acid) → a broad-spectrum antiseptic with a low risk of resistance, suitable for short-term use. An option when a patient firmly declines antibiotic treatment due to personal preference.

Hydrogel with METRONIDAZOLE (+ hyaluronic acid) → targeted antibacterial therapy for anaerobic infections; an antibiotic option for longer-term treatment. Also suitable when the patient is allergic to iodine.

Comparison from a pharmacological perspective

Criterion Hydrogel with Povidone-Iodine + Hyaluronic Acid Hydrogel with Metronidazole + Hyaluronic Acid
Active antibacterial agent Povidone-iodine (PVP-I) Metronidazole
Antimicrobial spectrum Bacteria (Gram-positive and Gram-negative), viruses, fungi, protozoa, spores Anaerobic bacteria, certain protozoa (*E. gingivalis, T. tenax*)
Mechanism of action Oxidises proteins and nucleic acids → rapid inhibition of microorganisms Penetrates anaerobic bacteria → damages DNA
Risk of resistance Practically none Possible, particularly with prolonged use
Onset of action Rapid (within minutes) Slower; depends on the activity of anaerobic microflora
Main indications Acute infected wounds, burns, ulcers, post-operative wounds Periodontitis, peri-implantitis, suppurative infections, abscesses, endodontic infections, after surgical procedures; may be used with other antibiotics and is often combined with amoxicillin (which targets aerobic bacteria)
Systemic absorption Possible → potential effects on thyroid function Negligible when applied locally
Duration / type of use Short-term use. For disinfection in cases of alveolitis after tooth extraction, periodontitis or post-operative suppuration. For infection control, up to 5 applications may be used in cases of acute inflammation or suppuration. Treatment.. For periodontitis, peri-implantitis, suppurative infections, abscesses, endodontic infections and after surgical procedures. May be used with other antibiotics and is often combined with amoxicillin (which targets aerobic bacteria). Can be applied to bone and into the implant site during implant placement and bone augmentation.
Effect on healing May delay granulation if used for prolonged periods Supports the healing process

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