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HYDROGEL WITH METRONIDAZOLE

A specially formulated hydrogel with metronidazole and hyaluronic acid, intended for the control and treatment of anaerobic infections, as well as for the treatment of peri-implantitis and periodontitis.

Metronidazole provides local infection control, while hyaluronic acid promotes tissue regeneration. The hydrogel is used during dental procedures in the clinic when a localized and prolonged effect of the active substances at the application site is required. Due to its structure, it adheres well to tissues, remains at the application site for an extended period and gradually releases the active substances. It is manufactured to individual orders from healthcare institutions at the compounding pharmacy of the Lithuanian University of Health Sciences.

The package contains 6 oral applicators with 1 ml of hydrogel each, 12 capillary application tips for precise and delicate application, and 12 metal application tips for use in harder-to-reach areas. One package is sufficient for up to 24 procedures (patients).

View the general application protocol HERE
Download the non-surgical peri-implantitis treatment protocol HERE

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Intended use:
For the treatment of periodontitis and peri-implantitis.
During oral and maxillofacial surgical procedures:
– Dental implant placement
– Bone and soft tissue augmentation
– Sinus floor elevation
– Complex tooth extraction
– Wisdom tooth extraction
– Removal of lesions from the oral cavity
– Other surgical procedures requiring additional wound disinfection

Methods of use:
Apply the hydrogel during surgery or immediately after the procedure – to periodontal pockets, the implant placement site, the wound or the gingival suture site. Distribute the hydrogel both on and around the wound. During the treatment of periodontitis or peri-implantitis, apply the hydrogel to the infected areas and the surrounding tissues.

Instructions for use:
Remove the protective cap from the oral applicator and attach a single-use application tip. Apply the required amount of hydrogel to the affected area. Using a spatula, gently spread the hydrogel over and around the affected area. If the wound is bleeding, apply a swab. After application, it is recommended not to rinse the mouth or eat for at least 1 hour.

Possible side effects:
The hydrogel must not be used in patients with known hypersensitivity to any of the substances contained in the product.

Storage conditions:
Do not use after the expiry date. Store at room temperature, away from direct sunlight.
For optimal results, it is recommended to continue care using other Fitodenta products: the Fitodenta Post-Operative Care Set, Fitodenta Oral Mucosal Spray or Gingival Gel. Additional information about the products is available at www.fitodenta.com

Manufacturer:
LSMU Pharmacy
Sukilėlių pr. 13, Kaunas, Lithuania

Product rights holder and order administrator:
Fitodenta, UAB
Raudondvario pl. 148, Kaunas, Lithuania
info@fitodenta.com
+370 686 69366
Expiry date: see packaging.
Scientific Research and Publications
Summary of scientific evidence on metronidazole for the protocol
Summary of scientific evidence on hyaluronic acid for the protocol
Clinical efficacy of local application of sustained-release metronidazole in periodontal therapy
The Effectiveness of Metronidazole as a Localized Drug Delivery System in the Treatment of Periodontal Diseases: A Narrative Review
Adjunctive use of hyaluronic acid in non-surgical periodontal therapy: A systematic review and meta-analysis
Role of hyaluronic acid in the treatment of peri-implant diseases: results of a meta-analysis
Metronidazols ir hialurona rūgštis odontologijā

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